DRAK2 (I286) polyclonal Antibody | BS9183

DRAK2 (I286) polyclonal Antibody | BS9183 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: DAP (death associated protein) kinase and ZIP kinase are members of a novel protein kinase family, the members of which have the capacity to mediate apoptosis through their catalytic activities. DAP kinase contains a “death domain” and has been shown to mediate γ interferon-induced apoptosis. The introduction of DAP kinase into highly metastatic carcinoma clones lacking DAP kinase expression was shown to result in the suppression of metastasis, thus linking suppression of apoptosis to metastasis. ZIP kinase contains a leucine zipper domain, which is necessary for homodimerization and for interaction with other leucine zipper proteins. ZIP kinase dimerizes with ATF-4, an ATF/CREB transcription factor family member that contains a leucine zipper. DRAK1 (DAP kinase-related apoptosis-inducing protein kinase 1) and DRAK2 are DAP kinase related proteins.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DRAK2 (I286) polyclonal Antibody detects endogenous levels of DRAK2 protein.

Molecular Weight: ~ 42 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: DAP kinase related apoptosis inducing protein; DAP kinase related apoptosis inducing protein kinase 2; DAP kinase-related apoptosis-inducing protein kinase 2; Death associated protein kinase related 2; DRAK 2; DRAK2; Serine/threonine kinase 17b; Serine/threonine kinase 17b apoptosis inducing; Serine/threonine protein kinase 17B; Serine/threonine-protein kinase 17B; ST17B; STK 17B; Stk17b;

Immunogen: Synthetic peptide, corresponding to amino acids 261-310 of Human DRAK2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: