763

DSC2 Polyclonal Antibody | E-AB-13194

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SKU:
763-763-E-AB-13194-GEN
NULL243.00 - NULL593.00

Description

DSC2 Polyclonal Antibody | E-AB-13194 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ARVD11, Cadherin family member 2, CDHF2, Desmocollin 3, Desmocollin-2, Desmocollin-3, Desmocollin2, Desmosomal glycoprotein II and III, Desmosomal glycoprotein II, Desmosomal glycoprotein II/III, Desmosomal glycoprotein III, DG2, DGII/III, DKFZp686I11137, DSC 2, DSC2, DSC2, DSC3

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular, Signal Transduction

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human DSC2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A

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