DSCR1 Antibody| F40133-0.08ML/F40133-0.4ML

DSCR1 Antibody| F40133-0.08ML/F40133-0.4ML | Gentaur UK, US & Europe Distribution

Background: DSCR1 (calcipressin 1) interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. Thr gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This DSCR1 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 75-104 from the human protein was used as the immunogen for this DSCR1 antibody.

Storage: Aliquot the DSCR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A