DTSSP Crosslinker | 2337

KEY FEATURES & APPLICATIONS: • Water-soluble • Has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends • Contains cleavable, 8-atom (12 Å) spacer arm • The disulfide bond in the spacer arm is cleavable with reducing agents such as DTT, TCEP, etc. • DTSSP crosslinker is membrane-impermeable, thus enabling cell-surface crosslinking without interfering with intercellular proteins

DTSSP is a cleavable homobifunctional protein crosslinking reagent

2337 | DTSSP Crosslinker DataSheet

Alternate Name/Synonyms: Sulfo-DSP DTBSSP disodium;1-[3-[[3-(2,5-dioxo-3-sulfonatopyrrolidin-1-yl)oxy-3-oxopropyl]disulfanyl]propanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 142702-31-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₄O₁₄N₂S₄Na₂

Molecular Weight: 608.51

Cell-Permeable?: Yes

Purity: ≥80% by NMR

Solubilities: H₂O (>6 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A cleavable homobifunctional protein crosslinking reagent

MDL Number: N/A

PubChem CID: 72386042

SMILES: C1C(C(=O)N(C1=O)OC(=O)CCSSCCC(=O)ON2C(=O)CC(C2=O)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+]

InChi: InChI=1S/C14H16N2O14S4.2Na/c17-9-5-7(33(23,24)25)13(21)15(9)29-11(19)1-3-31-32-4-2-12(20)30-16-10(18)6-8(14(16)22)34(26,27)28;;/h7-8H,1-6H2,(H,23,24,25)(H,26,27,28);;/q;2*+1/p-2

InChi Key: XRWWBWZHHSXBNC-UHFFFAOYSA-L