DUB Inhibitor, PR-619 | 2302

A cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs). Treatment of cells with PR-619 results in the accumulation of both ubiquitin and sumo-conjugated proteins.

PR-619 is a cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs).

2302 | DUB Inhibitor, PR-619 DataSheet

Alternate Name/Synonyms: 2,6-Diaminopyridine-3,5-bis(thiocyanate), 3,5-Dithiocyanatopyridine-2,6-diamine

Appearance: Yellow solid

Formulation: N/A

CAS Number: 2645-32-1

Structure Available?: Yes

Peptide sequence: No

Salt Form: No

Molecular Formula: C₇H₅N₅S₂

Molecular Weight: 223.28

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A deubiquitinylating enzymes (DUB) inhibitor

MDL Number: MFCD00830384

PubChem CID: N/A

SMILES: N#CSC1=C(N)N=C(N)C(SC#N)=C1

InChi: InChI=1S/C7H5N5S2/c8-2-13-4-1-5(14-3-9)7(11)12-6(4)10/h1H,(H4,10,11,12)

InChi Key: ZXOBLNBVNROVLC-UHFFFAOYSA-N