DUSP22 Polyclonal Antibody | E-AB-14065

DUSP22 Polyclonal Antibody | E-AB-14065 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Dual specificity protein phosphatase 22, DUS22, Dusp22, JNK stimulatory phosphatase 1, JNK-stimulatory phosphatase-1, JSP 1, JSP-1, JSP1, LMW DSP2, LMW-DSP2, Low molecular weight dual specificity phosphatase 2, MAP kinase phosphatase x, Mitogen activated protein kinase phosphatase x, Mitogen-activated protein kinase phosphatase x, MKP-x, MKPX

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Signal Transduction

Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human DUSP22

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A