DYNLT1 Antibody | 19-292

DYNLT1 Antibody | 19-292 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human DYNLT1 (NP_006510.1) .

Research Area: Other

Tested Application: WB

Application: WB: 1:200 - 1:2000

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: MCF7

Positive Control 3: Mouse thymus

Positive Control 4: Mouse heart

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 13kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CW-1, TCTEL1, tctex-1, dynein light chain Tctex-type 1, T-complex testis-specific protein 1 homolog, t-complex-associated-testis-expressed 1-like 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.