EBF2 Polyclonal Antibody | E-AB-19794

EBF2 Polyclonal Antibody | E-AB-19794 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: COE 2, COE2, COE2, Collier Olf and EBF 2, Early B cell factor 2, Early B-cell factor 2, EBF 2, EBF-2, Ebf2, FLJ11500, Metencephalon mesencephalnon olfactory transcription factor 1, O/E 3, O/E3, OE 3, OE3, OLF 1/EBF like 3, Transcription factor COE2

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Neuroscience

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

Concentration: 1.68 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human EBF2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 63 kDa

Molecular Weight(Observed): Refer to figures