EdU Cell Proliferation Image Kit (Orange Fluorescence) | KTA2031

EdU Cell Proliferation Image Kit (Orange Fluorescence) | KTA2031 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cellular states

Product Type: Apoptosis Detection Kit

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Kit Component: • Cell Lysis Buffer
• Reaction Buffer (2×)
• Ac-YVAD-pNA (4mM)
• pNA (10mM)
• DTT (100×)

Features & Benefits : • Simple and optimized procedure.
• Fast and convenient.
• Detect early/middle stages of apoptosis.

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Storage Conditions: Stable for at least 12 months at recommended temperature from date of shipment. Gel pack with blue ice.

Shipping: Gel pack with blue ice.

Background: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Mammalian caspases can be subdivided into three functional groups: initiator caspases (Caspase 2, 8, 9 and 10), executioner caspases (Caspase-3, 6 and 7), and inflammatory caspases (Caspase 1, 4, 5, 11 and 12) . Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of two inflammatory cytokines, interleukin-1β and IL-18 into active cytokines, initiating a proinflammatory response. It also cleaves Gasdermin D into its active form, which leads to pyroptosis.

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Tag: Caspase