EFCB7 Antibody (C-term) [AMM08621G]

EFCB7 Antibody (C-term) [AMM08621G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This EFCB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 434-462 amino acids from the C-terminal region of human EFCB7.

Cellular Localisation: Cell projection, cilium membrane {ECO:0000250|UniProtKB:Q8VDY4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8VDY4}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8VDY4}. Note=The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner. {ECO:0000250|UniProtKB:Q8VDY4}

Molecular Weight: 71981

Clone: Polyclonal

Gene Name: EFCAB7

Gene ID: 84455

Function: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: EF-hand calcium-binding domain-containing protein 7, EFCAB7, KIAA1799