EFNB1 Polyclonal Antibody | E-AB-53525

EFNB1 Polyclonal Antibody | E-AB-53525 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CFND, CFNS, Craniofrontonasal syndrome (craniofrontonasal dysplasia), EFL 3, EFL-3, EFL3, EFNB1, EFNB1, Elk L, ELK ligand, ELK-L, Eph related receptor tyrosine kinase ligand 2, EPH-related receptor tyrosine kinase ligand 2, Ephrin-B1, EPLG2, LERK 2, LERK-2, LERK2, Ligand of eph related kinase 2, MGC8782

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Cardiovascular, Developmental Biology, Neuroscience, Signal Transduction

Background: Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human EFNB1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A