EGFR Polyclonal Antibody | E-AB-63557

EGFR Polyclonal Antibody | E-AB-63557 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA

Application: WB, IF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human EGFR (NP_005219.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 44 kDa/69 kDa/77 kDa/134 kDa

Molecular Weight(Observed): 175 kDa