EHD4 polyclonal Antibody | BS72127

EHD4 polyclonal Antibody | BS72127 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB 1:500 - 1:2000

Background: Eps15 homology domain (EHD) -containing proteins function in the exit of receptors and other membrane proteins from the endosomal recycling compartment. EHD4 (Eps15 homology domain-containing protein 4), also known as PAST4 or Pincher, belongs to a subfamily of the EHD protein family that includes the closely related proteins EHD1, EHD2 and EHD3. EHD4 is predominantly expressed in pancreas and heart localizing to vesicular and tubular structures in the cell. It contains an EH domain as well as a calcium binding EF hand. EHD4 is believed to function in transport from the early endosome to the endocytic recycling compartment. In addition, EHD4 is capable of binding lipids via its EH domain. Loss of EHD4 can lead to retention of transferrin in peripheral compartments suggesting that EHD4 regulates the transport of transferrin out of the early endosome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: EHD4 polyclonal Antibody detects endogenous levels of EHD4 protein.

Molecular Weight: 72kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PAST4

Immunogen: Recombinant protein of human EHD4

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: