EHNA hydrochloride | 2265

A selective inhibitor of the cGMP-specific phosphodiesterase (PDE2) (IC₅₀s = 0.8 and 2 μM from human and porcine myocardium, respectively, 3.5 μM in rat hepatocyte, and 5.5 μM in human platelet). Also a reversible adenosine deaminase inhibitor (IC₅₀ = 1.2 μM in human red blood cells)

EHNA is a selective inhibitor of the cGMP-specific phosphodiesterase (PDE2) (IC₅₀s = 0.8 and 2 μM from human and porcine myocardium, respectively, 3.5 μM in rat hepatocyte, and 5.5 μM in human platelet).

2265 | EHNA hydrochloride DataSheet

Alternate Name/Synonyms: erythro-9-(2-Hydroxy-3-nonyl)adenine; (αR,​βS)-​rel-​6-​amino-​β-​hexyl-α-methyl-9H-purine-9-ethanol, monohydrochloride; NSC 263164

Appearance: White solid

Formulation: N/A

CAS Number: 58337-38-5

Structure Available?: Yes

Peptide sequence: No

Salt Form: No

Molecular Formula: C₁₄H₂₃N₅O ∙ HCl

Molecular Weight: 313.83

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>10 mg/ml) or H₂O (>10 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A cGMP-specific phosphodiesterase (PDE2) inhibitor

MDL Number: MFCD00151066

PubChem CID: 11957547

SMILES: CCCCCCC(C(C)O)N1C=NC2=C1N=CN=C2N.Cl

InChi: InChI=1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m1./s1

InChi Key: VVDXNJRUNJMYOZ-DHXVBOOMSA-N