EIF3H Polyclonal Antibody | E-AB-11182

EIF3H Polyclonal Antibody | E-AB-11182 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: eIF-3-gamma, eIF3 gamma, eIF3 p40, eIF3 p40 subunit, eIF3h, EIF3H, EIF3S3, Eukaryotic translation initiation factor 3 subunit 3, Eukaryotic translation initiation factor 3 subunit H, MGC102958

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: Eukaryotic translation initiation factor 3 subunit His aproteinthat in humans is encoded by theEIF3Hgene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human EIF3H

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A