EIF4A1 Monoclonal Antibody | E-AB-22076

EIF4A1 Monoclonal Antibody | E-AB-22076 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: ATP-dependent RNA helicase eIF4A-1, DDX2, DDX2A, eIF 4A I, eIF-4A-I, EIF4A, eIF4A I, eIF4A-I, EIF4A1, Eukaryotic initiation factor 4A-I, Eukaryotic initiation factor 4AI, eukaryotic translation initiation factor 4A, isoform 1, Eukaryotic translation initiation factor 4A1, IF4A1

Application: WB, IHC-p, IF

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:200

Clone: Clone:2B6

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): 48 kDa