eIF4G (Q1103) polyclonal Antibody | BS1534

eIF4G (Q1103) polyclonal Antibody | BS1534 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC IF

Application Range: IHC: 1:50~1:200 IF: 1:50~1:200

Background: The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E is a 25 kDa protein that binds to the mRNA “cap” during an early step in the initiation of protein synthesis. eIF4A acts as an ATP-dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A, and the eIF3 complex.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: eIF4G (Q1103) polyclonal Antibody detects endogenous levels of eIF4G protein.

Molecular Weight: N/A

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220; EIF4G1; 1981; EIF4G1; 600495; Q04637; DKFZp686A1451; EIF4F; EIF4G; p220;

Immunogen: Synthetic peptide, corresponding to amino acids 1080-1130 of Human eIF4G.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Nuclear Receptor Signaling,