Elagolix sodium | B2112

Elagolix sodium is a human GnRH (Gonadotropin-Releasing Hormone) receptor antagonist with an IC₅₀ and Ki of 0.25 and 3.7 nM, respectively. Elagolix alters the level of pituitary GnRH suppression and, as a result, titrating circulating estrogen levels.

Elagolix sodium is a human GnRH (Gonadotropin-Releasing Hormone) receptor antagonist with an IC₅₀ and Ki of 0.25 and 3.7 nM, respectively. Elagolix alters the level of pituitary GnRH suppression and, as a result, titrating circulating estrogen levels.

B2112 | Elagolix sodium DataSheet

Alternate Name/Synonyms: Sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate; NBI56418

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 832720-36-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₂H₂₉F₅N₃NaO₅

Molecular Weight: 653.57

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A human GnRH (Gonadotropin-Releasing Hormone) receptor antagonist

MDL Number: N/A

PubChem CID: 24785956

SMILES: CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)CC(C3=CC=CC=C3)NCCCC(=O)[O-])C4=C(C(=CC=C4)OC)F.[Na+]

InChi: InChI=1S/C32H30F5N3O5.Na/c1-19-28(21-11-6-14-26(45-2)29(21)34)30(43)40(18-25(20-9-4-3-5-10-20)38-16-8-15-27(41)42)31(44)39(19)17-22-23(32(35,36)37)12-7-13-24(22)33;/h3-7,9-14,25,38H,8,15-18H2,1-2H3,(H,41,42);/q;+1/p-1/t25-;/m0./s1

InChi Key: DQYGXRQUFSRDCH-UQIIZPHYSA-M