Elastase, Human Neutrophil | 4716

Elastase, like trypsin and chymotrypsin, is a serine protease that also hydrolyses amides and esters. It is produced in the pancreas as an inactive zymogen, proelastase, and activated in the duodenum by trypsin. Elastase is distinctive in that it acts upon elastin.This enzyme degrades elastin, collagen, and proteoglycan and has been implicated in the development of pulmonary emphesema and rheumatoid arthritis.

4716 | Elastase Human Neutrophil DataSheet

Biomolecule/Target: N/A

Synonyms: Leukocyte Elastase, ELA2

Alternates names: Leukocyte Elastase, ELA2

Taglines: Breaks down elastin

NCBI Gene ID #: 2246

NCBI Gene Symbol: FGF-1

Gene Source: N/A

Accession #: P05230

Recombinant: No

Source: Human Neutrophil

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): 20-22 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one micromole of Meo-Suc-Ala-Pro-Val-pNA per minute at 25°C in 100 mM Tris-HCl, pH 7.5, with 500 mM NaCl.

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 29.5 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Salt- free lyophilized solid

Reconstitution Instructions: Deionized HO

Amino acid sequence: N/A