ELFN1 Antibody (C-term) [APR15811G]

ELFN1 Antibody (C-term) [APR15811G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ELFN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 766-792 amino acids from the C-terminal region of human ELFN1.

Cellular Localisation: Membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Localizes to excitatory synapses onto somatostatin (Sst) -containing oriens-lacunosum moleculare (O-LM) interneurons

Molecular Weight: 90477

Clone: Polyclonal

Gene Name: ELFN1

Gene ID: 392617

Function: Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity) . Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Protein ELFN1, Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1, Protein phosphatase 1 regulatory subunit 28, ELFN1, PPP1R28