EMAP-II Inhibitor Z-ASTD-FMK | 1127

A synthetic peptide that irreversibly inhibits EMAP II (Endothelial Monocyte-Activated Polypeptide II) activity released during apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Z-ASTD-FMK is a cell-permeable, irreversible EMAP-II (Endothelial Monocyte-Activated Polypeptide II) inhibitor.

1127 | EMAP-II Inhibitor Z-ASTD-FMK DataSheet

Alternate Name/Synonyms: Z-ASTD-FMK, Z-ASTD-fluoromethylketone, EMAP-II Inhibitor(fluoromethylketone)

Appearance: Liquid

Formulation: DMSO (10 mM)

CAS Number: N/A

Structure Available?: No

Peptide sequence: Z-Ala-Ser-Thr-Asp(OMe)-FMK

Salt Form: No

Molecular Formula: C₂₄H₃₃FN₄O₁₀

Molecular Weight: 556.54

Cell-Permeable?: Yes

Purity: >99% by HPLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A EMAPII inhibitor

MDL Number: MFCD03453606

PubChem CID: 44134690

SMILES: CC(C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CO)NC(=O)C(C)NC(=O)OCC1=CC=CC=C1)O

InChi: InChI=1S/C24H33FN4O10/c1-13(26-24(37)39-12-15-7-5-4-6-8-15)21(34)28-17(11-30)22(35)29-20(14(2)31)23(36)27-16(18(32)10-25)9-19(33)38-3/h4-8,13-14,16-17,20,30-31H,9-12H2,1-3H3,(H,26,37)(H,27,36)(H,28,34)(H,29,35)

InChi Key: LICIOVKJUZZCAM-UHFFFAOYSA-N