Enalapril Maleate | B2131

Enalapril is a potent angiotensin converting-Enzyme (ACE) inhibitor used to treat for hypertension and heart failure. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation.

Enalapril is a potent angiotensin converting-Enzyme (ACE) inhibitor used to treat for hypertension and heart failure. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation.

B2131 | Enalapril Maleate DataSheet

Alternate Name/Synonyms: (S)-N-[1-(Ethoxycarbonyl)-3-phenylpropyl]-Ala-Pro maleate salt; Renitec; Glioten; Vasotec; Baripril

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 76095-16-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₈N₂O₅ · C₄H₄O₄

Molecular Weight: 492.52

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: H₂O (~25 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent angiotensin converting-Enzyme (ACE) inhibitor

MDL Number: MFCD00133304

PubChem CID: 5388961

SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O.C(=CC(=O)O)C(=O)O

InChi: InChI=1S/C20H28N2O5.C4H4O4/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25;5-3(6)1-2-4(7)8/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,16-,17-;/m0./s1

InChi Key: OYFJQPXVCSSHAI-QFPUQLAESA-N