BW
ENG (CD105) monoclonal Antibody | MB63153
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- BW-MB63153
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Description
ENG (CD105) monoclonal Antibody | MB63153 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Dog
Application: IF, WB
Application Range: WB 1:200~4000, IF 1:100
Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: endoglin
Molecular Weight: 65 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: END; HHT1; ORW1
Immunogen: Full length human recombinant protein of human ENG (NP_000109) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A