ENT1 (Slc29a1) Antibody (S254) [APR15841G]

ENT1 (Slc29a1) Antibody (S254) [APR15841G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This ENT1 (Slc29a1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-260 amino acids from human ENT1 (Slc29a1) .

Cellular Localisation: Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells

Molecular Weight: 50219

Clone: Polyclonal

Gene Name: SLC29A1

Gene ID: 2030

Function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter) . It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs) .

Summary: Tissue Location: Detected in erythrocytes (at protein level) . Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:500-1000

Synonyms: Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Equilibrative NBMPR-sensitive nucleoside transporter, Nucleoside transporter, es-type, Solute carrier family 29 member 1, SLC29A1, ENT1