Eotaxin/CCL11, human recombinant | 4028

Eotaxin is a recently discovered chemokine characterized by its high chemotactic selectivity for eosinophils. The position of the four cystein residues in Eotaxin places it in the C-C family of chemokines, along with chemokines such as RANTES, MCP-3, and MIP-1 alpha. The human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues. The sequence of the first five N-terminal amino acids is Gly-Pro-Ala-Ser-Val.

4028 | Eotaxin/CCL11 human recombinant DataSheet

Biomolecule/Target: Eotaxin

Synonyms: human Eotaxin

Alternates names: IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23

Taglines: A chemokine characterized by its high chemotactic selectivity for eosinophils

NCBI Gene ID #: 50929

NCBI Gene Symbol: IL22

Gene Source: Human

Accession #: Q9JJY9

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 97%

Assay: SDS-PAGE

Purity: 97%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: Recombinant murine IL-22 is fully biologically active when compared to a standard. The ED as determined by its ability to induce IL-10 secretion in Colo205 cells is less than 0.5 ng/ml, corresponding to a specific activity of 2 x 10 IU/mg.

Results: 10 ng/ ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 33.4 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from 20 mM phosphate buffer (pH 7.4) and 150 mM NaCl.

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1 to 1.0 mg/ml. This solution can then be stored at 4°C for 1 week or -20°C for future use. For long term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA). Avoid repeating freeze/thaw cycles.

Amino acid sequence: N/A