EpCAM polyclonal Antibody | BS90466

EpCAM polyclonal Antibody | BS90466 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC

Application Range: WB:1:500 ICC:1:100 IHC:1:50-1:200

Background: The epithelial cell adhesion molecule Ep-CAM, which is also designated tumor-associated calcium signal transducer 1 and MK-1, is a monomeric membrane glycoprotein that is expressed in most normal human epithelium and carcinomas. The human Ep-CAM gene encodes a 314 amino acid protein that is expressed as two forms, a major form and a minor form, which are reduced upon treatment with the amino-glycosylation inhibitor tunicamycin. Ep-CAM is overexpressed in a variety of carcinomas and is, therefore, a potential target for the visualization and therapy of human solid tumors. Ep-CAM contains an extracellular domain containing two epidermal growth factor-like repeats, followed by a cysteine poor region, which is necessary for the adhesion properties of the molecule.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: EpCAM polyclonal Antibody detects endogenous levels of EpCAM protein.

Molecular Weight: 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Ep-CAM, EGP, EGP314, hEGP314, EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1, 17 1A, 323/A3, Adenocarcinoma associated antigen, Adenocarcinoma-associated antigen, Antigen identified by monoclonal Antibody AUA1, AUA1, CD326, CD326 antigen, Cell surface glycoprotein Trop 1, Cell surface glycoprotein Trop 2, Cell surface glycoprotein Trop-1, CO 17A, CO17 1A, CO17A, DIAR5, EGP 2, EGP, EGP2, EGP314, EGP40, Ep CAM, Ep-CAM, EPCAM, EPCAM, EpCAM1, Epithelial cell adhesion molecule, Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD), Epithelial cell surface antigen, Epithelial cellular adhesion molecule, Epithelial glycoprotein 1, Epithelial glycoprotein 314, Epithelial glycoprotein, ESA, GA733 1, GA733 2, GA733-2, gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein, gp4, hEGP 2, hEGP314, HNPCC8, Human epithelial glycoprotein 2, KS 1/4 antigen, KS1/4, KSA, Ly74, Lymphocyte antigen 74, M1S 1, M1S2, M4S1 Antibody Major gastrointestinal tumor associated protein GA733 2 Antibody Major gastrointestinal tumor-associated protein GA733-2 Antibody mEGP314 Antibody Membrane component chromosome 4 surface marker (35kD glycoprotein) Antibody Membrane component, chromosome 4, surface marker 1 Antibody Membrane component, chromosome 4, surface marker Antibody MIC18 Antibody MK 1 Antibody Protein 289A Antibody TACD1 Antibody TACSTD1 Antibody TROP1 Antibody Tumor associated calcium signal transducer 1 Antibody Tumor associated calcium signal transducer 2 precursor Antibody Tumor-associated calcium signal transducer 1 Antibody

Immunogen: Synthetic peptide within human EpCAM 100-150 aa.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified.

Pathway: