EphB1/2/3/4 (Y594) polyclonal Antibody | BS3742

EphB1/2/3/4 (Y594) polyclonal Antibody | BS3742 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: IHC

Application Range: IHC: 1:50~1:200

Background: Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: EphB1/2/3/4 (Y594) polyclonal Antibody detects endogenous levels of EphB1/2/3/4 protein.

Molecular Weight: ~ 118 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: EphB1; EphB2; EphB3; EphB4;

Immunogen: Synthetic peptide, corresponding to amino acids 560-610 of Human EphB1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Insulin &Glucose Signaling,