Epirubicin Hydrochloride | 1753

Cell-permeable. An anthracycline antitumor antibiotic. A stereoisomer of doxorubicin (Cat. No. 1527-5) that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.

Epirubicin Hydrochloride is an anthracycline antitumor antibiotic. A stereoisomer of doxorubicin (Cat. No. 1527-5) that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.

1753 | Epirubicin Hydrochloride DataSheet

Alternate Name/Synonyms: (8S-cis)-10-((3-amino-2,3,6-trideoxy-β-L-arabino-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione hydrochloride; 4'-epiadriamycin; 4'-epidoxorubicin

Appearance: Orange-red powder

Formulation: N/A

CAS Number: 56390-09-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₇H₂₉NO₁₁ · HCl

Molecular Weight: 579.98

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: H₂O (1 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A DNA topoisomerase II inhibitor

MDL Number: MFCD00941448

PubChem CID: 65348

SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl

InChi: InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22-,27-;/m0./s1

InChi Key: MWWSFMDVAYGXBV-FGBSZODSSA-N