400

Epoxomicin, 100 µg

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SKU:
400-SIH-388-100UG-GEN
Availability:
IN STOCK
NULL528.00

Description

Epoxomicin, 100 µg

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Additional Information

Short Description:
Proteasome inhibitor
Research Area:
Cell Signaling
Alternative Name(s):
N-Acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-threoninamide
Category:
Small Molecules
Product Type:
Inhibitor
CAS No.:
134381-21-8
Molecular Formula:
C28H50N4O7
Molecular Weight:
554,7
Source:
Synthetic
Purity:
>95%
Solubility:
Soluble in DMSO (15 mg/ml) or dichloromethane:methanol (9:1); insoluble in water.
Appearance:
White solid
Storage:
-20ºC
Shipping:
Shipped Ambient
SMILES:
[C@@H](CC)(C)[C@@H](C(N[C@H](C(N[C@@H]([C@@H](C)O)C(=O)N[C@H](C(=O)NCC(=O)[C@]1(C)OC1)CC(C)C)=O)[C@H](CC)C)=O)N(C)C
InChI:
InChI=1S/C28H50N4O7/c1-11-16(5)21(30-27(38)23(17(6)12-2)32(10)19(8)34)25(36)31-22(18(7)33)26(37)29-20(13-15(3)4)24(35)28(9)14-39-28/h15-18,20-23,33H,11-14H2,1-10H3,(H,29,37)(H,30,38)(H,31,36)/t16-,17-,18+,20-,21-,22-,23-,28+/m0/s1
InChIKey:
DOGIDQKFVLKmlQ-JTHVHQAWSA-N
Field of Use:
For in vitro research use only.
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Originally isolated from Actinomycetes strain based on its potent in vivo antitumor activity, Epoxomicin is a potent, cell-permeable, selective and irreversible proteasome inhibitor. More potent...
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