Eptifibatide | 2439

A glycoprotein (GP) IIa/IIIb inhibitor. Eptifibatide inhibits platelet aggregation by reversibly binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets, thus preventing the binding of fibrinogen, von Willebrand factor, and other adhesive ligands. Inhibition of platelet aggregation occurs in a dose- and concentration-dependent manner.

Eptifibatide is a glycoprotein (GP) IIa/IIIb inhibitor. Eptifibatide inhibits platelet aggregation by reversibly binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets, thus preventing the binding of fibrinogen, von Willebrand factor, and other adhesive ligands.

2439 | Eptifibatide DataSheet

Alternate Name/Synonyms: Integrelin; Integrilin; Intrifiban

Appearance: White solid

Formulation: N/A

CAS Number: 188627-80-7

Structure Available?: Yes

Peptide sequence: [Mpa-Har-Gly-Asp-Trp-Pro-Cys]-NH₂

Salt Form: No

Molecular Formula: C₃₅H₄₉N₁₁O₉S₂

Molecular Weight: 831.96

Cell-Permeable?: No

Purity: ≥98%

Solubilities: H₂O (~ 5 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A glycoprotein (GP) IIa/IIIb inhibitor.

MDL Number: N/A

PubChem CID: 448812

SMILES: C1CC2C(=O)NC(CSSCCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N

InChi: InChI=1S/C35H49N11O9S2/c36-30(51)25-18-57-56-13-10-27(47)42-22(8-3-4-11-39-35(37)38)31(52)41-17-28(48)43-23(15-29(49)50)32(53)44-24(14-19-16-40-21-7-2-1-6-20(19)21)34(55)46-12-5-9-26(46)33(54)45-25/h1-2,6-7,16,22-26,40H,3-5,8-15,17-18H2,(H2,36,51)(H,41,52)(H,42,47)(H,43,48)(H,44,53)(H,45,54)(H,49,50)(H4,37,38,39)/t22-,23-,24-,25-,26-/m0/s1

InChi Key: CZKPOZZJODAYPZ-LROMGURASA-N