ERCC8 polyclonal Antibody | BS71908

ERCC8 polyclonal Antibody | BS71908 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse

Application: WB

Application Range: WB 1:500 - 1:2000

Background: This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS) . CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ERCC8 polyclonal Antibody detects endogenous levels of ERCC8 protein.

Molecular Weight: 44kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CKN1; CSA; UVSS2

Immunogen: A synthetic peptide of human ERCC8

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: