ERG/KCNH2 Polyclonal Antibody | BS65805

ERG/KCNH2 Polyclonal Antibody | BS65805 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,

Application: ICC,

Application Range: ICC=1:100-500

Background: The potassium voltage gated channel, subfamily H (eag related), member 2 (KCNH2) gene encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in KCNH2 have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. KCNH2 channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.Highly expressed in heart and brain.

Storage & Stability: Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles.

Specificity: ERG/KCNH2 Polyclonal Antibody detects endogenous levels of ERG/KCNH2 protein.

Molecular Weight: ~127 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ERG; ERG1; H ERG; HERG 1; HERG; HERG1; LQT 2; LQT2; Potassium channel HERG; SQT1; Voltagegated potassium channel, subfamily H, member 2; KCNH2_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human HERG:1001-1159/1159

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: