ERN2 Antibody (N-term) [APR05846G]

ERN2 Antibody (N-term) [APR05846G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-72 amino acids from the N-terminal region of human ERN2.

Cellular Localisation: Endoplasmic reticulum membrane; Single-pass type I membrane protein

Molecular Weight: 102480

Clone: Polyclonal

Gene Name: ERN2 (HGNC:16942)

Gene ID: 10595

Function: Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Serine/threonine-protein kinase/endoribonuclease IRE2, Endoplasmic reticulum-to-nucleus signaling 2, Inositol-requiring protein 2, hIRE2p, Ire1-beta, IRE1b, Serine/threonine-protein kinase, Endoribonuclease, 3126-, ERN2 (HGNC:16942)