ETAA1 Polyclonal Antibody | E-AB-17925

ETAA1 Polyclonal Antibody | E-AB-17925 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Etaa1, ETAA1, ETAA16, Ewing''s tumor-associated antigen 1, Ewing''s tumor-associated antigen 16

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology

Background: ETAA1 (Ewing's tumor-associated antigen 1), also known as ETAA16, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA1 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1, 400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstrom syndrome.

Concentration: 0.66 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ETAA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A