ETS1 Antibody (N-term) [APR03470G]

ETS1 Antibody (N-term) [APR03470G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ETS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human ETS1.

Cellular Localisation: Cytoplasm. Nucleus Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27.

Molecular Weight: 50408

Clone: Polyclonal

Gene Name: ETS1

Gene ID: 2113

Function: Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.

Summary: Tissue Location: Highly expressed within lymphoid cells. Isoforms c- ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: FC, IF, WB

Dilution: WB--1:1000 FC--1:10~50 IF--1:10~50

Synonyms: Protein C-ets-1, p54, ETS1, EWSR2