EXD2 Polyclonal Antibody | E-AB-18841

EXD2 Polyclonal Antibody | E-AB-18841 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 4930539P14Rik, C14orf114, C85658, DKFZp781A0133, DKFZp781L15100, Exd2, EXD2, EXDL2, Exonuclease 3''-5'' domain-containing protein 2, Exonuclease 3''-5'' domain-like-containing protein 2, exonuclease 3'-5' domain-like 2, FLJ10738, RGD1311087

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Concentration: 0.96 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human EXD2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 70 kDa

Molecular Weight(Observed): Refer to figures