ExoS | Exoenzyme S | AS05 056

ExoS | Exoenzyme S | AS05 056 | Gentaur UK, US & Europe Distribution

Immunogen: amino acids 366 to 453 of PA3841 of ADP-rbosylating enzyme - Exoenzyme S overexpressed in a GST fusion. Afterwards cleaved with a help of trombin and separated on a polyacrylamide gel. Gel piece has been used for immunizations.

Host: Chicken

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Purified, total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.

Format: Liquid

Tested Application: Western blot (WB)

Related Products: IMS01-133-332 | Anti-Pseudomonas aeruginosa, chicken antibodiesSecondary antibodies

Recommended Dilutions: 1 : 5000 (WB)

Molecular weight: 48 kDa

Confirmed Reactivity: Pseudomonas aeruginosa

Predicted Reactivity: Pseudomonas aeruginosa

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: N/A

Background: Exoenzyme S (ExoS) is a toxin directly translocated into eukaryotic cells by the type III secretory process of Pseudomonas aeruginosa. It is a bi-functional toxin and contain an N-terminal Rho GAP domain that disrupts the actin cytoskeleton and interference of phagocytosis. The C-terminal of ExoS contains an ADP-ribosyltransferase domain, which elicits a cytotoxic phenotype in cultured cells.

Reconstitution: N/A

Storage: Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Bacteria

Research Area: Bacteria