Ezrin polyclonal Antibody | BS90486

Ezrin polyclonal Antibody | BS90486 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC

Application Range: WB:1:500-1:1,000 IHC:1:50-1:200

Background: Ezrin, Moesin and Radixin belong to a family of highly homologous Actinassociated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70% homology with Ezrin and are coexpressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Ezrin polyclonal Antibody detects endogenous levels of Ezrin protein.

Molecular Weight: 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: EZR, Villin 2 ezrin, CVIL, CVL, Cytovillin 2, Cytovillin, DKFZp762H157, Epididymis secretory protein Li 105, EZR, EZRI, Ezrin, FLJ26216, HEL S 105, MGC1584, p81, VIL 2, VIL2, Villin 2 (ezrin), Villin 2, Villin-2, Villin2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: