EZSolution™ Brefeldin A | B1872

A 10 mM (5.0 mg in 1.78 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer Brefeldin A (Cat. No. 1560) in anhydrous DMSO.

Brefeldin A has been shown to induce apoptosis in human tumor cells through caspase activation. It has also been shown to block translocation of proteins from the endoplasmic reticulum to the Golgi apparatus.

B1872 | EZSolution™ Brefeldin A DataSheet

Alternate Name/Synonyms: Ascotoxin, BFA, Cyanein, Decumbin, γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone

Appearance: Liquid

Formulation: A 10 mM solution in DMSO

CAS Number: 20350-15-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₂₄O₄

Molecular Weight: 280.36

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and light

Country of Origin: USA

Tag Line: Disruptor of Golgi apparatus

MDL Number: MFCD12913297

PubChem CID: 2430

SMILES: CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O

InChi: InChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3

InChi Key: KQNZDYYTLMIZCT-UHFFFAOYSA-N