Description
INF39 is an irreversible and noncytotoxic NLRP3 inhibitor. It inhibits IL-1β release, caspase activation and pyroptosis in THP-1 cells.
INF39 is an irreversible and noncytotoxic NLRP3 inhibitor. It inhibits IL-1β release, caspase activation and pyroptosis in THP-1 cells.
B2530 | EZSolution™ INF39 DataSheet
Alternate Name/Synonyms: INF 39, Ethyl 2-(2-chlorobenzyl)acrylate
Appearance: Liquid
Formulation: A 10 mM ( 5 mg in 2.23 ml) solution in anhydrous DMSO
CAS Number: 866028-26-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₂H₁₃ClO₂
Molecular Weight: 224.68
Cell-Permeable?: True
Purity: ≥98%
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An irreversible NLRP3 inhibitor
MDL Number: MFCD27930542
PubChem CID: 69150705
SMILES: CCOC(=O)C(=C)CC1=CC=CC=C1Cl
InChi: InChI=1S/C12H13ClO2/c1-3-15-12(14)9(2)8-10-6-4-5-7-11(10)13/h4-7H,2-3,8H2,1H3
InChi Key: VTAOWWAFBSFWSG-UHFFFAOYSA-N