EZSolution™ Raptinal | 9652

A 10 mM (5 mg in 1294 µl) of the rapid apoptosis inducer Raptinal (Cat. No. 9626) in anhydrous DMSO.

Raptinal is a rapid inducer of apoptosis. Consistent with apoptotic morphological changes, U-937 cells treated with 10 μM Raptinal displays modest (at 30 min) and extensive (at 60 min) blebbing. Consistent with caspase-dependent apoptosis, the pan-caspase inhibitor Q-VD-OPh (Cat. No. 1170) quantitatively blocks the loss in cell viability and cellular blebbing. Raptinal is also found to induce death against various cancer and non-cancerous cell lines with 24 hour IC₅₀ values between 0.7-3.4 μM indicating activity across a wide variety of cell lines.

9652 | EZSolution™ Raptinal DataSheet

Alternate Name/Synonyms: 9H, 9’H-[9,9’-bifluorene]-9,9’-dicarbaldehyde

Appearance: Liquid

Formulation: A 10 mM solution in DMSO

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₁₈O₂

Molecular Weight: 386.44

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A rapid inducer of apoptosis

MDL Number: N/A

PubChem CID: N/A

SMILES: O=CC1(C2(C=O)C3=CC=CC=C3C4=C2C=CC=C4)C5=CC=CC=C5C6=C1C=CC=C6

InChi: InChI=1S/C28H18O2/c29-17-27(23-13-5-1-9-19(23)20-10-2-6-14-24(20)27)28(18-30)25-15-7-3-11-21(25)22-12-4-8-16-26(22)28/h1-18H

InChi Key: GLANOOJJBKXTMI-UHFFFAOYSA-N