EZSolution™ RepSox | 2641

A 10 mM (5 mg in 1740 µl) of the ALK5 inhibitor RepSox (Cat. No. 1894) in anhydrous DMSO.

RepSox is a TGF-β type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC₅₀ = 4 nM). Can replace one of the four reprogramming factors Sox-2.

2641 | EZSolution™ RepSox DataSheet

Alternate Name/Synonyms: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452

Appearance: Liquid

Formulation: N/A

CAS Number: 446859-33-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₃N₅

Molecular Weight: 287.32

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A TGF-β type I receptor (ALK5) inhibitor

MDL Number: MFCD09037561

PubChem CID: 449054

SMILES: CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4

InChi: InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15 (21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)

InChi Key: LBPKYPYHDKKRFS-UHFFFAOYSA-N