FA96A Antibody (C-term) [APR30756G]

FA96A Antibody (C-term) [APR30756G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This FA96A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the C-terminal region of human FA96A.

Cellular Localisation: Cytoplasm.

Molecular Weight: 18355

Clone: Polyclonal

Gene Name: CIAO2A (HGNC:26235)

Gene ID: 84191

Function: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004) . As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004) . May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227) .

Summary: Tissue Location: Substantially enriched in macrophages.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, IF

Dilution: WB--1:2000

Synonyms: MIP18 family protein FAM96A, FAM96A