Factor IX Polyclonal Antibody | E-AB-14396

Factor IX Polyclonal Antibody | E-AB-14396 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Christmas Disease, Christmas factor, Coagulant factor IX, Coagulation factor 9, Coagulation factor IX, Coagulation factor IXa heavy chain, F9, FA9, Factor 9, Factor IX Deficiency, FactorIX, FIX, Haemophilia B, HEMB, MGC129641, MGC129642, P19, Plasma Thromboplastic Component, Plasma thromboplastin component, PTC

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular, Immunology

Background: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human F9

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 52 kDa

Molecular Weight(Observed): N/A