Factor VII, Human Plasma | 7686

Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid (gla) residues located in the NH2-terminal portion of the molecule, which facilitate cell membrane binding. Factor VII is proteolytically activated to the serine protease, factor VIIa, during coagulation. Factor VII can be activated by thrombin, factor IXa, factor Xa or factor XIIa.

7686 | Factor VII Human Plasma DataSheet

Biomolecule/Target: Factor VII

Synonyms: Proconvertin, Serum prothrombin conversion accelerator.

Alternates names: Proconvertin, Serum prothrombin conversion accelerator.

Taglines: Responsible for starting a cascade of proteolytic events that lead to thrombin generation, fibrin deposition, and platelet activation.

NCBI Gene ID #: 2247

NCBI Gene Symbol: FGF-2

Gene Source: Human

Accession #: P09038

Recombinant: No

Source: Human Plasma

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Lot dependent

Results: Lot dependent

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 50 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: In 20 mM Tris-HCl, 0.1 M NaCl, 1 mM Benzamidine, pH 7.4.

Reconstitution Instructions: N/A

Amino acid sequence: N/A