FAM111B polyclonal Antibody | BS61053

FAM111B polyclonal Antibody | BS61053 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: FAM111B is a 734 amino acid protein that is encoded by a gene that maps to human chromosome 11, which makes up around 4% of human genomic DNA and isconsidered a gene and disease association dense chromosome.The chromosome 11 encoded Atmgene isimportant for regulation ofcellcycle arrest and apoptosisfollowing double strand DNA breaks. Atmmutation leads to the disorderknown as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB genemutations. Wilms’ tumors, WAGR syndrome and Denys-Drash syndrome are associatedwithmutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associatedwith defectsin chromosome 11.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FAM111B polyclonal Antibody detects endogenous levels of FAM111B protein.

Molecular Weight: ~ 81 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Protein FAM111B; Cancer-associated nucleoprotein; FAM111B; CANP

Immunogen: A synthetic peptide corresponding to residues in Human FAM111B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: