FAM168B Antibody (C-term) [APR32968G]

FAM168B Antibody (C-term) [APR32968G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This FAM168B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the C-terminal region of human FAM168B.

Cellular Localisation: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:D4AEP3}. Cell membrane {ECO:0000250|UniProtKB:Q80XQ8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q80XQ8}. Cell projection, axon {ECO:0000250|UniProtKB:Q80XQ8}. Note=Expressed in neuronal cell bodies and axonal fibers. {ECO:0000250|UniProtKB:Q80XQ8}

Molecular Weight: 20324

Clone: Polyclonal

Gene Name: FAM168B

Gene ID: 130074

Function: Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27.

Summary: Tissue Location: Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level) . Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Myelin-associated neurite-outgrowth inhibitor, Mani, p20, FAM168B, KIAA0280L, MANI