FAM92A1 Antibody (Center) [APR05579G]

FAM92A1 Antibody (Center) [APR05579G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This FAM92A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human FAM92A1.

Cellular Localisation: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium {ECO:0000250|UniProtKB:Q8BP22}. Note=Weak punctate vesicular distribution throughout the cytoplasm (PubMed:27528616) . Localizes at the distal end of mother centrioles (PubMed:27528616) . Extensive colocalization with CBY1 at mother centrioles (PubMed:27528616)

Molecular Weight: 33431

Clone: Polyclonal

Gene Name: FAM92A (HGNC:30452)

Gene ID: 137392

Function: Acts as a positive regulator of ciliary hedgehog signaling (By similarity) . Probable regulator of ciliogenesis involved in limb morphogenesis. In cooperation with CBY1 it is involved in the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Protein FAM92A1, FAM92A1