FAP polyclonal Antibody | BS90492

FAP polyclonal Antibody | BS90492 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB ICC FC

Application Range: WB:1:500-1:1,000 ICC:1:50-1:200 FC:1:50-1:100

Background: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Plays a role in tissue remodeling during development and wound healing. Participates in the cell invasiveness towards the ECM in malignant melanoma cancers. Enhances tumor growth progression by increasing angiogenesis, collagen fiber degradation and apoptosis and by reducing antitumor response of the immune system. Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: FAP polyclonal Antibody detects endogenous levels of FAP protein.

Molecular Weight: 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FAPalpha, SIMP, Seprase, APCE, Adenomatous Polyposis Coli, Adenomatous polyposis coli protein, Apc, APC, CC1, Deleted in polyposis 2.5, DP2, DP2.5, DP3, FAP, FPC, GS, Protein APC,

Immunogen: Peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: