FASTKD3 Antibody (C-term) [APR15921G]

FASTKD3 Antibody (C-term) [APR15921G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This FASTKD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-650 amino acids from the C-terminal region of human FASTKD3.

Cellular Localisation: Mitochondrion

Molecular Weight: 75689

Clone: Polyclonal

Gene Name: FASTKD3

Gene ID: 79072

Function: Required for normal mitochondrial respiration (PubMed:20869947) . Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity (PubMed:27789713) .

Summary: Tissue Location: Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: FAST kinase domain-containing protein 3, FASTKD3